Episode 153: COMT - Why Some Nervous Systems Feel Everything More Intensely

June 25, 2026 00:13:00
Episode 153: COMT - Why Some Nervous Systems Feel Everything More Intensely
The Chronic Fatigue and Burnout Recovery Podcast
Episode 153: COMT - Why Some Nervous Systems Feel Everything More Intensely

Jun 25 2026 | 00:13:00

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Hosted By

Anna Marsh

Show Notes

Some people notice that they seem to experience stimulation and stress more intensely than others.

They may feel overwhelmed in busy environments, react strongly to caffeine, or find it difficult to switch off mentally after a demanding day.

Sometimes people encounter the term COMT when exploring genetic testing and begin to wonder whether this might explain their nervous system sensitivity.

But conversations about COMT online can quickly become confusing — and sometimes unnecessarily alarming.

In this episode, Anna explores what COMT actually does in the body, how it influences the way we process certain stress-related brain chemicals, and why some nervous systems naturally experience stimulation more strongly than others.

Most importantly, we discuss why COMT is not a defect, but rather a pattern of biological sensitivity that can have both challenges and strengths.

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Website: http://annamarsh.co.uk/

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